1 standard vape pod does not directly equal 20 packs of cigarettes in terms of nicotine content, but it can contain nicotine equivalent to a pack of cigarettes. A JUUL pod, for How Many Puffs of Vape is Equal to a Cigarette? UPENDS Nicotine formula used by e cigarette maker Juul is nearly identical to the flavor and addictive profile of Marlboro cigarettes : r science How Many Puffs in a Juul Pod? A Guide to Flavor and Longevity Inline Vape LLC What Does A JUUL Really Do To Your Body? Franciscan Health