Pigmented Lesions of the Oral Cavity Pocket Dentistry Melanocytic Lesions A Guide to Clinical Differential Diagnosis of Oral Mucosal Lesions Continuing Education Course dentalcare.com Oral Melanotic Macule: Symptoms and Treatment Skinsight Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360