The impact of glutathione metabolism in autism spectrum disorder ScienceDirect Tylenol, Autism, And The Glutathione Connection OC Integrative Medicine Tylenol can lower the body's key antioxidant, glutathione, though this isn't seen on routine labs. But mechanistic data clinical proof, so we still need good trials. The Tylenolautism link isn't clear. I'm not suggesting that there's a definitive link between Tylenol and autism, but it 100% depletes your body of glutathione, and enough studies have shown that it should only be taken when Acetaminophen Use During Pregnancy and Autism Risk