Pigmented Lesions of the Oral Mucosa Pocket Dentistry Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier Hunziker syndrome Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Melanotic Macules, Naevi, and Melanoma Springer Nature Link Pigmented Lesions of the Oral Mucosa Springer Nature Link