We all know smoking and vaping isn't great for your health. But it doesn't stop you from being a blood or plasma donor. Just make sure to wait one hour after donating Does cannabis create thirdhand smoke? Thirdhand Smoke Resource Center Severe bleeding linked to synthetic cannabinoid use Texas Poison Center Network Can You Donate Plasma If You Smoke Weed? NuggMD Smoking and vaping don't affect your eligibility to donate. Become a donor and give life today.